Low intensity ultrasound perturbs cytoskeleton dynamics

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Low intensity ultrasound perturbs cytoskeleton dynamics.

Therapeutic ultrasound is widely employed in clinical applications but its mechanism of action remains unclear. Here we report prompt fluidization of a cell and dramatic acceleration of its remodeling dynamics when exposed to low intensity ultrasound. These physical changes are caused by very small strains (10-5) at ultrasonic frequencies (106 Hz), but are closely analogous to those caused by r...

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Low Intensity Pulsed Ultrasound (LIPUS)

The application of ultrasound energy at much lower levels than is the current clinical norm is starting to gain ground as a therapeutic possibility. Clearly the applied energy is the same, it is the ‘dose’ which is different – most importantly, the intensity (W cm) – which is MUCH lower – typically 2 or 3 times lower than the lowest setting on most regular clinical machines, with the most commo...

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Low Intensity Pulsed Ultrasound (LIPUS)

The application of ultrasound energy at much lower levels than is the current clinical norm is starting to gain ground as a therapeutic possibility. Clearly the applied energy is the same, it is the ‘dose’ which is different – most importantly, the intensity (W/cm) – which is MUCH lower – typically 2 or 3 times lower than the lowest setting on most regular clinical machines, with the most commo...

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ژورنال

عنوان ژورنال: Soft Matter

سال: 2012

ISSN: 1744-683X,1744-6848

DOI: 10.1039/c2sm07246g